Computational Regulatory Genomics

Are you sure you want to delete: << Promoting developmental transcription >> ?
<< YES >>       << NO >>

Promoting developmental transcription

Uwe Ohler,  D. Wassarman 
Development 2010 137 1 15--26 PubMed Central   DOI   PubMed  


Animal growth and development depend on the precise control of gene expression at the level of transcription. A central role in the regulation of developmental transcription is attributed to transcription factors that bind DNA enhancer elements, which are often located far from gene transcription start sites. Here, we review recent studies that have uncovered significant regulatory functions in developmental transcription for the TFIID basal transcription factors and for the DNA core promoter elements that are located close to transcription start sites.
This site is covered by the MDC Data Privacy policy